Do you ever wonder how your physician chooses an appropriate medication for you? Do you feel overwhelmed by the sheer number of accessible medications? These tips will help recognize the choices that can be found. In subsequent articles, there will be information about each class of medication. health jade
While there are hundreds of medications and combinations of medications available, there are seven different classes of medication. Each class works in another way to. Your physician uses his knowledge a person as well as being the specific type of diabetes to with if you need any medication, and in case so, which class to use. Took place . chooses a medication from that study course. If you require medication from more than one class he should prescribe more than a single medication or a mix pill which has two or more medications contained involved with it. This article will offering a brief overview of the classes of medications and how they work.
1.) The oldest class of medicine is the sulfonylureas. Prior to the mid-1990s, this was the only class of oral medications available. Your body must be place produce insulin strategy to for these with regard to beneficial, as they work by stimulating the beta cells of the pancreas to secrete insulin. Some examples of the first generation of these medications are: Tolbutamide (orinase), Tolinase (tolazamide), and Diabinese (chlorpropamide). Some of important generation medications are: Glipizide (glucatrol), extended release Glipizide (glucatrol XL), Glyburide (Micronase, Diabeta), Glynase (micronized glyburide), and Glimepiride. These medications are distinguished by how long they last as body, and if they are cleared through the kidney or the liver. There are two other drugs in this class: Prandin and Starlix, which can be used before meals purely because they last for the most short time.
2.) The biguanide class has only one medication, called Metformin. Other names are Fortamet, Glucophage, Gluymetza, and Riomet. This medication works by decreasing glucose production in the liver, and in addition, it causes a small increase in glucose uptake by skeletal muscle. If there aren’t any contraindications, the American Diabetes Association and also the American college of clinical endocrinologists recommends using this medication first.
3.) In the mid-1990s, the Thiazolidinedione class of medications (also known as glitizones or TZDs) was developed. Their primary mechanism of action is maximize insulin sensitivity, which results in more glucose being taken up by skeletal muscle. Three medications were developed. The first, Rezulin (troglitazone), was taken off the market because it was suggested to result in liver problems. The second, Avandia (rosiglitazone), was withdrawn from the market in Europe but was allowed under selling restrictions in the US because of a rise in cardiovascular events. 3rd workout medication, Actos (pioglitazone) had sales suspended in France and Germany because a study suggested it might increase the risk of bladder cancer.
4.) Drugs affecting the incretin system are divided into two subclasses:
a. The first division is made from injectable drugs which mimic the effect of natural incretins produced by no less than. Medications in this class include Byetta (exenetide), Bydureon (long acting exenatide) Victoza (liraglutide), and Symlin. They work by increasing insulin secretion in reply to glucose (sugar), reducing the rate at in which the liver puts out glucose, decreasing appetite, and by slowing the rate the stomach empties. These medications have become quite popular if they can help with weight loss, and just have an extremely low incidence of hypoglycemia. However, these medications have been in news reports because they happen to associated with pancreatitis, and may create a slight increase in medullary thyroid cancers.
b. The oral medications in this class work by blocking the enzyme which breaks down the incretins. While the condition of natural incretins increases somewhat, these medicines are not as effective as the injectable ones. Medications in this class include Januvia (sitagliptin), Onglyza (saxagliptin), and Tradjenta. They are being observed to watch out for complications similar towards injectable medications. They very rarely cause hypoglycemia and do not cause weight gather. They are all being evaluated as a potential cancer hazard.
5.) There are three Alpha Glucosidase Inhibitors: Acarbose (Precose), Miglitol (Glyset), and Voglibose. These work by preventing digestion of carbohydrates your intestine. By preventing carbohydrates from being converted into simple sugars and absorbed into the blood stream from the intestine, this class of medications can help keep the blood sugar from rising after meals.
6.) The newest class of medications is the SGLT2 inhibitors, which block absorption of glucose by the elimination. By increasing the amount of glucose lost through the urine, and lowering the amount of sugar absorbed back into the blood stream, blood may be decreased. Because none of these medications already been approved by the FDA, the names of the medications are omitted designed by this article.
7.) Insulin can be used for people with type I Diabetes and is often needed for those with type 2 Diabetic. There are many types and delivery systems which will be going to discussed subsequently.
With a thorough understanding of your specific type of diabetes, your physician can wade through all the options to pick best match an individual. More detailed information about each drug class will be provided in subsequent articles here, and smaller website, diabeticsurvivalkit.com. Feedback visit at that whenever for information about medications, cooking videos featuring diabetic meal and dessert recipes, and current news articles.